How to use Mifeprex?
Buy Mifepristone online, this tablet which must be consumed orally with water. Generally this medication can be taken once in a day. Tablets should not be crushed, chewed or spitted.
Drug description
Buy Mifeprex online, this tablet consists of 200mg mifepristone, which is a synthetic steroid bearing antiprogestational property. This tablet appears in light yellowish color. Tablet looks cylindrical in shape having bi-convex sides. Mifeprex contains few inactive ingredients such as magnesium stearate, colloidal silica anhydrous, microcrystalline cellulose, corn starch.
This compound looks like yellow colored powder of molecular weight 429.6. Melting point of this compound is about 192-196°C. Buy Mifepristone online which is highly soluble in acetone, chloroform and methanol. It is less soluble in hexane, isopropyl ether and water.
Dosage
Depending upon medical conditions, other medicines consumption and response to the treatment are considered for deciding the dosage. You should also tell details of the non prescribed medicines, prescribed medicines, herbal products to your pharmacist. For the reduction of risk initially pharmacist might suggest low doses and eventually dosage will be increased.
For better benefits buy Mifepristone online and take it every day. If once the intake of this drug stopped then person may need to start from the lower dose eventually take the higher doses. When you have not consumed the drug for many days then you may need to consult pharmacist or doctor for the guidance on restarting the medicine.
Action mechanism
Buy Mifeprex online, this pill is an antiprogestin as it avidly binds to the receptor progesterone without activating it. Norethindrone is a progestine whose structure is similar to mifepristone. Hence mifepristone binds avidly to the progesterone receptors with great or equal affinity than progesterone.
The adding up of bulky side chain at the 11th position of carbon renders mifepristone to be inactive as a progestin. Due to this mifepristone blocks all the activities of progesterone at the receptor levels.
Around 18 hours after intake of some high dose mifepristone regimes taken in the duration of early pregnancy, trophoblast seperates from decidua, in maternal circulation decline it is levels of β-HCG. Locally the prostaglandins gets released.this medication also induces rhythemic uterine contractions and cervical ripening. It leads to uterine bleeding.
Side Effects
Intake of this drug may cause dry mouth, headache, tiredness, dizziness, reduced appetite, vomiting or nausea, pain in muscles or joints. If the person experiences any of the mentioned effects then contact pharmacist and discuss regarding the effects. Most of the people who take this drug do not have any severe side effects. If you find side effects like unusual bleeding in vagina, swollen hands or ankles or feet, reduced levels of potassium in the blood causing weakness and muscle cramps, shortness of breath then immediately you need to contact doctor. If this medication triggers any allergic reactions then one must take proper treatment. In rare cases if you find any other side effects then consult doctor.
Precautions
If you’ve any allergies you need to talk to your doctor before the intake of mifeprex. Buy Mifepristone online and it can contain the ingredients which are inactive and they may trigger allergies or other problems in rare scenarios. Discussion regarding your medical history with the pharmacist is recommended in cases of kidney disorders, vaginal bleed, endometrical cancer, heart disorders, imbalance in minerals in the body, elevated levels of blood pressure. Intake of mifepristone may cause dizziness so avoid driving, using machineries and limit the alcohol consumption. This medication may also causes QT prolongation in rare cases this action may cause severe irregular heartbeats. If the condition worsens then consult doctor immediately.
In rare scenarios the QT prolongation risk may get elevated in some medical conditions or some other drugs consumption. So before taking this drug, consult your pharmacist or doctor and talk about your health issues to avoid serious reactions which may cause irregular heartbeats. If the potassium content is observed lower levels in the body then also there are chances of QT prolongation risk. Aged people are considerably more sensitive to the side effects of Mifepristone. During pregnancy this medication should not be taken as it may causes pregnancy loss. Avoid this drug if your breast feeding, because this drug passes into the breast milk which can cause health issues for baby. Person must avoid the consumption of grape fruit or its juice during the medication. Grape fruit may show adverse reactions with Mifeprex.
Interactions of Mifeprex are as follows:
Change in the interactions of mifepristopne may depend upon how medications work in your body or it may elevate your risk of severe side effects. So you need to share the drugs details history with pharmacist to avoid such risk. Person should not stop, start or change the dose of this medication without the guidance of pharmacist. This drug reacts with corticosteroids like prednisone.
In the body this medication can slow down the removal of other drugs. This can affect how it normally works. Some examples of affected medications contains ergot alkaloids like dihydroergotamine and ergotamine, quinidine, fentanyl, cyclosporine, pimozide, few statin medications( lovastatin, simvastatin, fluvastatin), tacrolimus, sirolimus, warfarin, among other drugs.Some medicines like HIV protease inhibitors, azole antifungals, macrolide antibiotics, boceprevir, nefazodone alters the actions of mifepristone. Mifepristone reduces the effectiveness of hormonal birth control system such as patch, pills or the ring. In such scenarios there may be chances of pregnancy. Few of the beta-blocker drugs like timolol(glaucoma eye drops) , propranolol, metoprolol can cause irregular heartbeats while the sugar level in blood falls to lower levels. Some symptoms of low blood sugar levels like sweating, dizziness, hunger are not affected by these medications. One must also monitor the diabetic medication, healthy diet and fitness exercise programs.
Overdose
Overdose intake of this medication can turn out as poisonous, so avoid high doses without the recommendation of pharmacist. If you’ve taken overdose then immediately contact doctor.
Missed Dose
In any case if you missed a regular dose, remind yourself to take the medication as soon as you remember. in case if the time is close to the time of the next dose intake then it is recommended to skip the missed dose and resume to your regular schedule of dose intake. To balance don’t try to double the dosage.
Storage
Buy Mifeprex online and it should be stored away from moisture and light at room temperature. Never store this drug in bathrooms. Store this medicine away from children and animals. Avoid flushing tablets in toilet or throwing them to drainages. If the medicine is not needed or expired then discard it properly.